KATP channel-dependent regulation of glucagon release from mouse and human pancreatic alpha-cells

KATP channel-dependent regulation of glucagon release from mouse and human pancreatic alpha-cells

Bibliografiska uppgifter
Huvudupphovsmän:	Rorsman, P, MacDonald, P, Ramracheya, R, Johnson, P
Materialtyp:	Journal article
Publicerad:	2007

Liknande verk

Regulation of glucagon release in mouse -cells by KATP channels and inactivation of TTX-sensitive Na+ channels.
av: Göpel, S, et al.
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A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.
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A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans
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Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes.
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A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.
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Expression of GABA(A) receptor Cl- channels and glucose-dependent GABA release in human pancreatic islets
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Evidence from in situ human alpha-cells supporting intrinsic K-ATP channel-dependent regulation of glucagon secretion
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Publicerad: (2006)

Effects of glucose, GLP-1 and adrenaline on alpha cell electrical activity and glucagon secretion from mouse pancreatic islets
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Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta-cells.
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Glucagon stimulates exocytosis in mouse and rat pancreatic alpha-cells by binding to glucagon receptors.
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ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells.
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Regulation of glucagon release from pancreatic A-cells.
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Membrane potential-dependent inactivation of voltage-gated ion channels in alpha-cells inhibits glucagon secretion from human islets.
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K(ATP)-channels and glucose-regulated glucagon secretion.
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ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: Similar functions but reciprocal effects on secretion
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ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: similar functions but reciprocal effects on secretion.
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Elevation of cAMP promotes an Epac2 dependent, L-type Ca2+-channel coupled, Ca2+-induced Ca2+ release in mouse alpha cells
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GLP-1 suppresses glucagon secretion in human pancreatic alpha-cells by inhibition of P/Q-type Ca2+ channels
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Publicerad: (2018)

Scn3a encodes the functionally important Na+-channel alpha-subunit (Nav 1.3) in mouse pancreatic alpha and beta cells
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Palmitate stimulation of glucagon secretion in mouse pancreatic alpha-cells results from activation of L-type calcium channels and elevation of cytoplasmic calcium.
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KATP channels and islet hormone secretion: New insights and controversies
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Tolbutamide stimulates exocytosis of glucagon by inhibition of a mitochondrial-like ATP-sensitive K+ (KATP) conductance in rat pancreatic A-cells.
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Dual effects of low and high concentrations of cAMP on glucagon secretion from mouse pancreatic A-cells
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Glucose in glucagon release.
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SUBSTRATE-DEPENDENT CHANGES IN MITOCHONDRIAL-FUNCTION, [CA-2+]I AND KATP CHANNELS IN MOUSE PANCREATIC BETA-CELLS INVITRO
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Per-arnt-sim (PAS) domain kinase (PASK) as a regulator of glucagon secretion.
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Per-arnt-sim (PAS) domain kinase (PASK) as a regulator of glucagon secretion
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GLP-1 inhibits glucagon secretion from human alpha cells by a direct effect
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Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?
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Imidazoline NNC77-0074 stimulates insulin secretion and inhibits glucagon release by control of Ca(2+)-dependent exocytosis in pancreatic alpha- and beta-cells.
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Structural insights into the mechanism of pancreatic KATP channel regulation by nucleotides
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Publicerad: (2022-05-01)

The Structural Basis for the Binding of Repaglinide to the Pancreatic KATP Channel
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Publicerad: (2019-05-01)

Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.
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Action of incretins on the pancreatic alpha cell
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KATP channel dependent heart multiome atlas
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The glucagon-producing alpha cell: an electrophysiologically exceptional cell.
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Insulin prevents counter-regulatory glucagon secretion by stimulation of somatostatin release
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Regulation of KATP channel activity
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Memantine has no effect on KATP channels in pancreatic β cells
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Publicerad: (2018-08-01)

Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes.
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