Increased prevalence of Listeria monocytogenes in the faeces of patients receiving long-term H2-antagonists.
BACKGROUND: Human listeriosis is an uncommon infection caused by the Gram-positive organism Listeria monocytogenes. OBJECTIVE: To investigate the effects of therapeutic gastric acid suppression on faecal isolation of L. monocytogenes and the incidence of human listeriosis. METHODS: Five stool speci...
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Journal article |
| Kieli: | English |
| Julkaistu: |
1996
|
| _version_ | 1826299876426645504 |
|---|---|
| author | Cobb, C Curtis, G Bansi, D Slade, E Mehal, W Mitchell, R Chapman, R |
| author_facet | Cobb, C Curtis, G Bansi, D Slade, E Mehal, W Mitchell, R Chapman, R |
| author_sort | Cobb, C |
| collection | OXFORD |
| description | BACKGROUND: Human listeriosis is an uncommon infection caused by the Gram-positive organism Listeria monocytogenes. OBJECTIVE: To investigate the effects of therapeutic gastric acid suppression on faecal isolation of L. monocytogenes and the incidence of human listeriosis. METHODS: Five stool specimens from each of 20 patients on continuous H2-antagonist therapy and two faecal samples from each of 47 healthy controls were investigated for the presence of Listeria spp. RESULTS: A higher faecal isolation rate of L. monocytogenes was detected amongst the patients (20%) compared with the controls (2.1%) (P < 0.025). All subjects with stools positive for Listeria spp. were female, this sex difference being significant in the patient group (P < 0.0036) compared with controls. No patient, however, developed listeriosis. CONCLUSION: Patients on long-term gastric acid suppressive therapy may be at increased risk of faecal carriage of L. monocytogenes. |
| first_indexed | 2024-03-07T05:08:38Z |
| format | Journal article |
| id | oxford-uuid:dac9db39-10fb-482a-904a-3d08ff3b9b40 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:08:38Z |
| publishDate | 1996 |
| record_format | dspace |
| spelling | oxford-uuid:dac9db39-10fb-482a-904a-3d08ff3b9b402022-03-27T09:05:44ZIncreased prevalence of Listeria monocytogenes in the faeces of patients receiving long-term H2-antagonists.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:dac9db39-10fb-482a-904a-3d08ff3b9b40EnglishSymplectic Elements at Oxford1996Cobb, CCurtis, GBansi, DSlade, EMehal, WMitchell, RChapman, R BACKGROUND: Human listeriosis is an uncommon infection caused by the Gram-positive organism Listeria monocytogenes. OBJECTIVE: To investigate the effects of therapeutic gastric acid suppression on faecal isolation of L. monocytogenes and the incidence of human listeriosis. METHODS: Five stool specimens from each of 20 patients on continuous H2-antagonist therapy and two faecal samples from each of 47 healthy controls were investigated for the presence of Listeria spp. RESULTS: A higher faecal isolation rate of L. monocytogenes was detected amongst the patients (20%) compared with the controls (2.1%) (P < 0.025). All subjects with stools positive for Listeria spp. were female, this sex difference being significant in the patient group (P < 0.0036) compared with controls. No patient, however, developed listeriosis. CONCLUSION: Patients on long-term gastric acid suppressive therapy may be at increased risk of faecal carriage of L. monocytogenes. |
| spellingShingle | Cobb, C Curtis, G Bansi, D Slade, E Mehal, W Mitchell, R Chapman, R Increased prevalence of Listeria monocytogenes in the faeces of patients receiving long-term H2-antagonists. |
| title | Increased prevalence of Listeria monocytogenes in the faeces of patients receiving long-term H2-antagonists. |
| title_full | Increased prevalence of Listeria monocytogenes in the faeces of patients receiving long-term H2-antagonists. |
| title_fullStr | Increased prevalence of Listeria monocytogenes in the faeces of patients receiving long-term H2-antagonists. |
| title_full_unstemmed | Increased prevalence of Listeria monocytogenes in the faeces of patients receiving long-term H2-antagonists. |
| title_short | Increased prevalence of Listeria monocytogenes in the faeces of patients receiving long-term H2-antagonists. |
| title_sort | increased prevalence of listeria monocytogenes in the faeces of patients receiving long term h2 antagonists |
| work_keys_str_mv | AT cobbc increasedprevalenceoflisteriamonocytogenesinthefaecesofpatientsreceivinglongtermh2antagonists AT curtisg increasedprevalenceoflisteriamonocytogenesinthefaecesofpatientsreceivinglongtermh2antagonists AT bansid increasedprevalenceoflisteriamonocytogenesinthefaecesofpatientsreceivinglongtermh2antagonists AT sladee increasedprevalenceoflisteriamonocytogenesinthefaecesofpatientsreceivinglongtermh2antagonists AT mehalw increasedprevalenceoflisteriamonocytogenesinthefaecesofpatientsreceivinglongtermh2antagonists AT mitchellr increasedprevalenceoflisteriamonocytogenesinthefaecesofpatientsreceivinglongtermh2antagonists AT chapmanr increasedprevalenceoflisteriamonocytogenesinthefaecesofpatientsreceivinglongtermh2antagonists |