New structural insights into the inhibition of serine proteases by cyclic peptides from bacteria.

The inhibition of enzymes employing a nucleophilic serine residue by natural products has been studied for many years. More recently, high-resolution structural analyses have begun to augment kinetic analyses. In this issue of Chemistry and Biology, Schulz and colleagues describe the crystal structu...

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Détails bibliographiques
Auteurs principaux: McDonough, M, Schofield, C
Format: Journal article
Langue:English
Publié: 2003