New structural insights into the inhibition of serine proteases by cyclic peptides from bacteria.

The inhibition of enzymes employing a nucleophilic serine residue by natural products has been studied for many years. More recently, high-resolution structural analyses have begun to augment kinetic analyses. In this issue of Chemistry and Biology, Schulz and colleagues describe the crystal structu...

Descrizione completa

Dettagli Bibliografici
Autori principali: McDonough, M, Schofield, C
Natura: Journal article
Lingua:English
Pubblicazione: 2003