New structural insights into the inhibition of serine proteases by cyclic peptides from bacteria.

The inhibition of enzymes employing a nucleophilic serine residue by natural products has been studied for many years. More recently, high-resolution structural analyses have begun to augment kinetic analyses. In this issue of Chemistry and Biology, Schulz and colleagues describe the crystal structu...

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Detalhes bibliográficos
Main Authors: McDonough, M, Schofield, C
Formato: Journal article
Idioma:English
Publicado em: 2003