Structural organization of the 19S proteasome lid: insights from MS of intact complexes.

Structural organization of the 19S proteasome lid: insights from MS of intact complexes.

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The 26S proteasome contains a 19S regulatory particle that selects and unfolds ubiquitinated substrates for degradation in the 20S catalytic particle. To date there are no high-resolution structures of the 19S assembly, nor of the lid or base subcomplexes that constitute the 19S. Mass spectra of the...

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Autors principals:	Sharon, M, Taverner, T, Ambroggio, X, Deshaies, R, Robinson, C
Format:	Journal article
Idioma:	English
Publicat:	2006

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