CD4 T cells from malaria-nonexposed individuals respond to the CD36-Binding Domain of Plasmodium falciparum erythrocyte membrane protein-1 via an MHC class II-TCR-independent pathway.

We have studied the human CD4 T cell response to a functionally conserved domain of Plasmodium falciparum erythrocyte membrane protein-1, cysteine interdomain region-1alpha (CIDR-1alpha). Responses to CIDR-1alpha were striking in that both exposed and nonexposed donors responded. The IFN-gamma respo...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Ndungu, F, Sanni, L, Urban, B, Stephens, R, Newbold, C, Marsh, K, Langhorne, J
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2006