Selection bias at the heterosexual HIV-1 transmission bottleneck
Heterosexual transmission of HIV-1 typically results in one genetic variant establishing systemic infection.We compared, for 137 linked transmission pairs, the amino acid sequences encoded by non-envelope genes of viruses in both partners and demonstrate a selection bias for transmission of residues...
Główni autorzy: | Carlson, J, Schaefer, M, Monaco, D, Batorsky, R, Claiborne, D, Prince, J, Deymier, M, Ende, Z, Klatt, N, DeZiel, C, Lin, T, Peng, J, Seese, A, Shapiro, R, Frater, J, Ndung'u, T, Tang, J, Goepfert, P, Gilmour, J, Price, M, Kilembe, W, Heckerman, D, Goulder, P, Allen, T, Allen, S |
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Format: | Journal article |
Język: | English |
Wydane: |
American Association for the Advancement of Science
2014
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