Selection bias at the heterosexual HIV-1 transmission bottleneck

Selection bias at the heterosexual HIV-1 transmission bottleneck

Heterosexual transmission of HIV-1 typically results in one genetic variant establishing systemic infection.We compared, for 137 linked transmission pairs, the amino acid sequences encoded by non-envelope genes of viruses in both partners and demonstrate a selection bias for transmission of residues...

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Bibliographic Details
Main Authors:	Carlson, J, Schaefer, M, Monaco, D, Batorsky, R, Claiborne, D, Prince, J, Deymier, M, Ende, Z, Klatt, N, DeZiel, C, Lin, T, Peng, J, Seese, A, Shapiro, R, Frater, J, Ndung'u, T, Tang, J, Goepfert, P, Gilmour, J, Price, M, Kilembe, W, Heckerman, D, Goulder, P, Allen, T, Allen, S
Format:	Journal article
Language:	English
Published:	American Association for the Advancement of Science 2014

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