Selection bias at the heterosexual HIV-1 transmission bottleneck
Heterosexual transmission of HIV-1 typically results in one genetic variant establishing systemic infection.We compared, for 137 linked transmission pairs, the amino acid sequences encoded by non-envelope genes of viruses in both partners and demonstrate a selection bias for transmission of residues...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
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| 格式: | Journal article |
| 語言: | English |
| 出版: |
American Association for the Advancement of Science
2014
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