Negative selection on BRCA1 susceptibility alleles sheds light on the population genetics of late-onset diseases and aging theory

Negative selection on BRCA1 susceptibility alleles sheds light on the population genetics of late-onset diseases and aging theory

Taispeáin leaganacha eile (1)

The magnitude of negative selection on alleles involved in age-specific mortality decreases with age. This is the foundation of the evolutionary theory of senescence. Because of this decrease in negative selection with age, and because of the absence of reproduction after menopause, alleles involved...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Pavard, S, Metcalf, C
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	Public Library of Science 2007

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