Age-related clonal hematopoiesis associated with adverse outcomes.

Age-related clonal hematopoiesis associated with adverse outcomes.

BACKGROUND: The incidence of hematologic cancers increases with age. These cancers are associated with recurrent somatic mutations in specific genes. We hypothesized that such mutations would be detectable in the blood of some persons who are not known to have hematologic disorders. METHODS: We anal...

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Main Authors: Jaiswal, S, Fontanillas, P, Flannick, J, Manning, A, Grauman, P, Mar, BG, Lindsley, R, Mermel, C, Burtt, N, Chavez, A, Higgins, J, Moltchanov, V, Kuo, F, Kluk, M, Henderson, B, Kinnunen, L, Koistinen, H, Ladenvall, C, Getz, G, Correa, A, Banahan, B, Gabriel, S, Kathiresan, S, Stringham, H, McCarthy, M
Format: Journal article
Language:English
Published: Massachussetts Medical Society 2014

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