Mutations in Exon 1 Highlight the Role of MED12 in Uterine Leiomyomas

Mutations in Exon 1 Highlight the Role of MED12 in Uterine Leiomyomas

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Mediator regulates transcription by connecting gene-specific transcription factors to the RNA polymerase II initiation complex. We recently discovered by exome sequencing that specific exon 2 mutations in mediator complex subunit 12 (MED12) are extremely common in uterine leiomyomas. Subsequent scre...

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Bibliographic Details
Main Authors:	Kämpjärvi, K, Park, M, Mehine, M, Kim, N, Clark, A, Bützow, R, Böhling, T, Böhm, J, Mecklin, J, Järvinen, H, Tomlinson, I, van der Spuy, Z, Sjöberg, J, Boyer, T, Vahteristo, P
Format:	Journal article
Language:	English
Published:	Wiley 2014

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