Factors influencing sib risks for multiple sclerosis.
Multiple sclerosis (MS) is now thought to be a complex trait determined by genetic and non-genetic (environmental) factors. The study group, identified from the Canadian Collaborative Project on Genetic Susceptibility to MS, consisted of 1,083 MS index cases, 2,166 of their parents and 3,112 of thei...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2000
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| _version_ | 1797098453308801024 |
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| author | Sadovnick, A Yee, I Ebers, G |
| author_facet | Sadovnick, A Yee, I Ebers, G |
| author_sort | Sadovnick, A |
| collection | OXFORD |
| description | Multiple sclerosis (MS) is now thought to be a complex trait determined by genetic and non-genetic (environmental) factors. The study group, identified from the Canadian Collaborative Project on Genetic Susceptibility to MS, consisted of 1,083 MS index cases, 2,166 of their parents and 3,112 of their sibs. The results, together with those of a previous study on an independent data set, suggest that gender, age of MS onset and having one parent with MS may individually and interactively alter sib risks for MS. These data are important for genetic counselling and for molecular genetic (genome screens, candidate gene analyses) studies. |
| first_indexed | 2024-03-07T05:09:46Z |
| format | Journal article |
| id | oxford-uuid:db2bfa56-0836-4509-b471-84c92711fddc |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:09:46Z |
| publishDate | 2000 |
| record_format | dspace |
| spelling | oxford-uuid:db2bfa56-0836-4509-b471-84c92711fddc2022-03-27T09:08:32ZFactors influencing sib risks for multiple sclerosis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:db2bfa56-0836-4509-b471-84c92711fddcEnglishSymplectic Elements at Oxford2000Sadovnick, AYee, IEbers, GMultiple sclerosis (MS) is now thought to be a complex trait determined by genetic and non-genetic (environmental) factors. The study group, identified from the Canadian Collaborative Project on Genetic Susceptibility to MS, consisted of 1,083 MS index cases, 2,166 of their parents and 3,112 of their sibs. The results, together with those of a previous study on an independent data set, suggest that gender, age of MS onset and having one parent with MS may individually and interactively alter sib risks for MS. These data are important for genetic counselling and for molecular genetic (genome screens, candidate gene analyses) studies. |
| spellingShingle | Sadovnick, A Yee, I Ebers, G Factors influencing sib risks for multiple sclerosis. |
| title | Factors influencing sib risks for multiple sclerosis. |
| title_full | Factors influencing sib risks for multiple sclerosis. |
| title_fullStr | Factors influencing sib risks for multiple sclerosis. |
| title_full_unstemmed | Factors influencing sib risks for multiple sclerosis. |
| title_short | Factors influencing sib risks for multiple sclerosis. |
| title_sort | factors influencing sib risks for multiple sclerosis |
| work_keys_str_mv | AT sadovnicka factorsinfluencingsibrisksformultiplesclerosis AT yeei factorsinfluencingsibrisksformultiplesclerosis AT ebersg factorsinfluencingsibrisksformultiplesclerosis |