An N-ethyl-n-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess
Cushing's syndrome, which is characterized by excessive circulating glucocorticoid concentrations, maybe due to ACTH-dependent or -independent causes that include anterior pituitary and adrenal cortical tumors, respectively. ACTH secretion is stimulated by CRH, and we report a mouse model for C...
Hlavní autoři: | Bentley, L, Esapa, C, Nesbit, M, Head, R, Evans, H, Lath, D, Scudamore, C, Hough, T, Podrini, C, Hannan, F, Fraser, W, Croucher, P, Brown, M, Brown, S, Cox, R, Thakker, R |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2014
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