Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease.

Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease.

In vascular disease states such as atherosclerosis and diabetes, endothelial nitric oxide (NO) bioactivity is reduced and oxidative stress is increased, resulting in endothelial dysfunction. Recent studies suggest that changes in the activity and regulation of endothelial NO synthase by its cofactor...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας:	Channon, K
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2004

Παρόμοια τεκμήρια

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Tetrahydrobiopterin protects against hypertrophic heart disease independent of myocardial nitric oxide synthase coupling
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Adenovirus-mediated GTP cyclohydrolase I gene delivery augments tetrahydrobiopterin and restores nitric oxide synthase function in hyperglycaemic human aortic endothelial cells
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Tetrahydrobiopterin: a vascular redox target to improve endothelial function.
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Post-translational Regulation of Endothelial Nitric Oxide Synthase in Vascular Endothelium
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Critical role of vascular peroxidase 1 in regulating endothelial nitric oxide synthase
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P683The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy.
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