Genetic variability of the forkhead box O3 and prostate cancer risk in the European Prospective Investigation on Cancer.

Genetic variability of the forkhead box O3 and prostate cancer risk in the European Prospective Investigation on Cancer.

Forkhead box O3 (FOXO3) has a wide range of functions: it promotes tumor suppression, cell cycle arrest, repair of damaged DNA, detoxification of reactive oxygen species, apoptosis and plays a pivotal role in promoting longevity. FOXO3 is a key downstream target of the PI3K-Akt pathway in response t...

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Autors principals:	Campa, D, Hüsing, A, Dostal, L, Stein, A, Drogan, D, Boeing, H, Tjønneland, A, Roswall, N, Østergaard, J, Overvad, K, Rodríguez, L, Bonet, C, Sánchez, M, Larrañaga, N, Huerta, J, Ardanaz, E, Khaw, K, Wareham, N, Travis, R, Allen, N, Trichopoulou, A, Zylis, D, Karapetyan, T, Palli, D, Sieri, S
Format:	Journal article
Idioma:	English
Publicat:	2011

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