Genetic variability of the forkhead box O3 and prostate cancer risk in the European Prospective Investigation on Cancer.

Genetic variability of the forkhead box O3 and prostate cancer risk in the European Prospective Investigation on Cancer.

Forkhead box O3 (FOXO3) has a wide range of functions: it promotes tumor suppression, cell cycle arrest, repair of damaged DNA, detoxification of reactive oxygen species, apoptosis and plays a pivotal role in promoting longevity. FOXO3 is a key downstream target of the PI3K-Akt pathway in response t...

Description complète

Détails bibliographiques
Auteurs principaux: Campa, D, Hüsing, A, Dostal, L, Stein, A, Drogan, D, Boeing, H, Tjønneland, A, Roswall, N, Østergaard, J, Overvad, K, Rodríguez, L, Bonet, C, Sánchez, M, Larrañaga, N, Huerta, J, Ardanaz, E, Khaw, K, Wareham, N, Travis, R, Allen, N, Trichopoulou, A, Zylis, D, Karapetyan, T, Palli, D, Sieri, S
Format: Journal article
Langue:English
Publié: 2011

Documents similaires

Documents similaires