HIV-1 Vpu represents a minor target for cytotoxic T lymphocytes in HIV-1-infection.

HIV-1 Vpu represents a minor target for cytotoxic T lymphocytes in HIV-1-infection.

We have previously shown that Vpu is rarely targeted by HIV-1-specific cytotoxic T lymphocytes (CTL). The present report extends these findings and describes the characterization of the first CTL epitope within HIV-1 Vpu, identified in an individual with long-term non-progressive HIV-1 infection. Th...

Bibliográfalaš dieđut
Váldodahkkit:	Addo, M, Altfeld, M, Rathod, A, Yu, M, Yu, X, Goulder, P, Rosenberg, E, Walker, B
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2002

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Dahkki: Borrow, P, et al.
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