Set2 methyltransferase facilitates DNA replication and promotes genotoxic stress responses through MBF-dependent transcription
Chromatin modification through histone H3 lysine 36 methylation by the SETD2 tumor suppressor plays a key role in maintaining genome stability. Here, we describe a role for Set2-dependent H3K36 methylation in facilitating DNA replication and the transcriptional responses to both replication stress a...
主要な著者: | , , , , , , , , , , |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
Cell Press
2017
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