Set2 methyltransferase facilitates DNA replication and promotes genotoxic stress responses through MBF-dependent transcription

Set2 methyltransferase facilitates DNA replication and promotes genotoxic stress responses through MBF-dependent transcription

Chromatin modification through histone H3 lysine 36 methylation by the SETD2 tumor suppressor plays a key role in maintaining genome stability. Here, we describe a role for Set2-dependent H3K36 methylation in facilitating DNA replication and the transcriptional responses to both replication stress a...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Pai, C, Kishkevich, A, Deegan, R, Keszthelyi, A, Folkes, L, Kearsey, S, De León, N, Soriano, I, de Bruin, R, Carr, A, Humphrey, T
التنسيق: Journal article
اللغة:English
منشور في: Cell Press 2017

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