Genetic susceptibility to coronary artery disease: from promise to progress.
Family history is an important independent risk factor for coronary artery disease (CAD), and identification of susceptibility genes for this common, complex disease is a vital goal. Although there has been considerable success in identifying genetic variants that influence well-known risk factors,...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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| _version_ | 1797098554211172352 |
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| author | Watkins, H Farrall, M |
| author_facet | Watkins, H Farrall, M |
| author_sort | Watkins, H |
| collection | OXFORD |
| description | Family history is an important independent risk factor for coronary artery disease (CAD), and identification of susceptibility genes for this common, complex disease is a vital goal. Although there has been considerable success in identifying genetic variants that influence well-known risk factors, such as cholesterol levels, progress in unearthing novel CAD genes has been slow. However, advances are now being made through the application of large-scale, systematic, genome-wide approaches. Recent findings particularly highlight the link between CAD and inflammation and immunity, and highlight the biological insights to be gained from a genetic understanding of the world's biggest killer. |
| first_indexed | 2024-03-07T05:11:15Z |
| format | Journal article |
| id | oxford-uuid:db9fcdcc-eb7a-4bd4-a8fa-df02c1d70034 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:11:15Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:db9fcdcc-eb7a-4bd4-a8fa-df02c1d700342022-03-27T09:11:56ZGenetic susceptibility to coronary artery disease: from promise to progress.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:db9fcdcc-eb7a-4bd4-a8fa-df02c1d70034EnglishSymplectic Elements at Oxford2006Watkins, HFarrall, MFamily history is an important independent risk factor for coronary artery disease (CAD), and identification of susceptibility genes for this common, complex disease is a vital goal. Although there has been considerable success in identifying genetic variants that influence well-known risk factors, such as cholesterol levels, progress in unearthing novel CAD genes has been slow. However, advances are now being made through the application of large-scale, systematic, genome-wide approaches. Recent findings particularly highlight the link between CAD and inflammation and immunity, and highlight the biological insights to be gained from a genetic understanding of the world's biggest killer. |
| spellingShingle | Watkins, H Farrall, M Genetic susceptibility to coronary artery disease: from promise to progress. |
| title | Genetic susceptibility to coronary artery disease: from promise to progress. |
| title_full | Genetic susceptibility to coronary artery disease: from promise to progress. |
| title_fullStr | Genetic susceptibility to coronary artery disease: from promise to progress. |
| title_full_unstemmed | Genetic susceptibility to coronary artery disease: from promise to progress. |
| title_short | Genetic susceptibility to coronary artery disease: from promise to progress. |
| title_sort | genetic susceptibility to coronary artery disease from promise to progress |
| work_keys_str_mv | AT watkinsh geneticsusceptibilitytocoronaryarterydiseasefrompromisetoprogress AT farrallm geneticsusceptibilitytocoronaryarterydiseasefrompromisetoprogress |