Single-dose immunogenicity and protective efficacy of simian adenoviral vectors against Plasmodium berghei.
Simian adenoviral vectors (SAd) offer an attractive alternative to standard human adenovirus serotype 5 (AdH5) subunit vaccination, due to pre-existing immunity affecting vaccine performance. We have used a mouse model of liver-stage malaria to test the efficiency of three chimpanzee-origin adenovir...
Main Authors: | Reyes-Sandoval, A, Sridhar, S, Berthoud, T, Moore, A, Harty, J, Gilbert, S, Gao, G, Ertl, H, Wilson, J, Hill, A |
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Format: | Journal article |
Language: | English |
Published: |
2008
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