Modeling chromosomal translocations using conditional alleles to recapitulate initiating events in human leukemias.

Modeling chromosomal translocations using conditional alleles to recapitulate initiating events in human leukemias.

Recurrent reciprocal chromosomal translocations are present in more than 50% of leukemias. A deeper understanding of how they affect cancer initiation is essential for evaluating the origins of cancer and the potential for therapy based on the translocation products. Mouse models of chromosomal tran...

書誌詳細
主要な著者:	Lobato, M, Metzler, M, Drynan, L, Forster, A, Pannell, R, Rabbitts, T
フォーマット:	Journal article
言語:	English
出版事項:	2008

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