Tetrahydrobiopterin-dependent eNOS coupling mediates endothelial regeneration and attenuates vein graft atherosclerosis in ApoE-KO mice

Tetrahydrobiopterin-dependent eNOS coupling mediates endothelial regeneration and attenuates vein graft atherosclerosis in ApoE-KO mice

Bibliografiske detaljer
Main Authors:	Ali, Z, Alp, N, Hu, Y, Xiao, Q, Akthar, A, Douglas, G, Tatham, A, deBono, J, Greaves, D, Xu, Q, Channon, K
Format:	Conference item
Udgivet:	2007

Lignende værker

Increased eNOS coupling protects against vein graft accelerated atherosclerosis in ApoE-KO mice
af: Ali, Z, et al.
Udgivet: (2006)

Increased endothelial tetrahydrobiopterin synthesis reduces vein graft atherosclerosis in ApoE-knockout mice
af: Ali, Z, et al.
Udgivet: (2005)

Tetrahydrobiopterin-dependent eNOS coupling determines vascular remodeling through accelerated endothelial regeneration
af: Ali, Z, et al.
Udgivet: (2007)

Increased endothelial tetrahydrobiopterin synthesis reduces vein graft accelerated atherosclerosis in apolipoprotein E-knockout mice
af: Ali, Z, et al.
Udgivet: (2006)

Tetrahydrobiopterin-dependent eNOS coupling attenuates vein graft atherosclerosis through inhibition of MCP-1 mediated monocyte recruitment to sites of vascular injury
af: Ali, Z, et al.
Udgivet: (2007)

Tetrahydrobiopterin availability directly regulates eNOS coupling in tet-regulatable cells
af: Crabtree, M, et al.
Udgivet: (2007)

Regulation of eNOS function by tetrahydrobiopterin in vascular disease
af: Channon, K
Udgivet: (2004)

Long-term oral tetrahydrobiopterin supplementation reduces atherosclerosis in apolipoprotein E-KO mice
af: Schmidt, T, et al.
Udgivet: (2008)

Regulation of endothelial nitric oxide synthase (eNOS) by tetrahydrobiopterin in vascular disease
af: Alp, N, et al.
Udgivet: (2004)

Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.
af: Cai, S, et al.
Udgivet: (2005)

Endothelial-targeted GTP cyclohydrolase I overexpression increases endothelial tetrahydrobiopterin levels and preserves eNOS coupling in eNOS overexpressing mice
af: Bendall, J, et al.
Udgivet: (2004)

Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression.
af: Crabtree, M, et al.
Udgivet: (2009)

Tetrahydrobiopterin deficiency increases susceptibility to atherosclerosis
af: Khoo, J, et al.
Udgivet: (2005)

Endothelial tetrahydrobiopterin (BH4) regulates eNOS coupling in vivo: Functional effects of BH4-eNOS stoichiometry in endothelial targeted transgenic mice
af: Bendall, J, et al.
Udgivet: (2005)

Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression.
af: Bendall, J, et al.
Udgivet: (2005)

Endothelial tetrahydrobiopterin regulates eNOS coupling/uncoupling independent of vascular disease: Insights from targeted transgenic models
af: Bendall, J, et al.
Udgivet: (2004)

Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.
af: Alp, N, et al.
Udgivet: (2004)

CCR2-mediated antiinflammatory effects of endothelial tetrahydrobiopterin inhibit vascular injury-induced accelerated atherosclerosis.
af: Ali, Z, et al.
Udgivet: (2008)

Single dose oral tetrahydrobiopterin (BH4) leads to a prolonged increase in aortic BH4 levels in ApoE-KO mice
af: Schmidt, T, et al.
Udgivet: (2007)

5-methyl-tetrahydrofolate increases eNOS activity by preventing peroxynitrite-induced oxidation of tetrahydrobiopterin in human vessels
af: Antoniades, C, et al.
Udgivet: (2006)

Tetrahydrobiopterin- and glutathionylation-dependent regulation of eNOS coupling: Relationships revealed by eNOS glutathionylation mutants in cells with tet-regulated GTP cyclohydrolase I expression
af: Crabtree, M, et al.
Udgivet: (2012)

Tetrahydrobiopterin supplementation reduces atherosclerosis and vascular inflammation in apolipoprotein E-knockout mice.
af: Schmidt, T, et al.
Udgivet: (2010)

Mononuclear cell therapy attenuates atherosclerosis in apoE KO mice
af: Meyrelles Silvana S, et al.
Udgivet: (2011-09-01)

Broad spectrum adenoviral CC-chemokine blockade attenuates long term vein graft accelerated atherosclerosis in ApoE-knockout mice
af: Ali, Z, et al.
Udgivet: (2007)

A pivotal role for tryptophan 447 in enzymatic coupling of human endothelial nitric oxide synthase (eNOS): effects on tetrahydrobiopterin-dependent catalysis and eNOS dimerization.
af: Benson, M, et al.
Udgivet: (2013)

Tetrahydrobiopterin determines vascular remodeling through enhanced endothelial cell survival and regeneration.
af: Ali, Z, et al.
Udgivet: (2013)

RAPID, DIRECT EFFECTS OF STATIN TREATMENT ON ARTERIAL REDOX STATE AND NITRIC OXIDE BIOAVAILABILITY IN HUMAN ATHEROSCLEROSIS VIA TETRAHYDROBIOPTERIN-MEDIATED ENOS COUPLING
af: Antoniades, C, et al.
Udgivet: (2011)

Intravenous infusion of 5-methyl-tetrahydrofolate rapidly improves eNOS Coupling. In human vessels by increasing tetrahydrobiopterin bioavailability
af: Antoniades, C, et al.
Udgivet: (2006)

Endothelial cell tetrahydrobiopterin: going with the flow.
af: De Bono, J, et al.
Udgivet: (2007)

In-stent restenosis and atherosclerosis in a human saphenous vein graft.
af: Alp, N, et al.
Udgivet: (2003)

In-stent restenosis and atherosclerosis in a human saphenous vein graft.
af: Alp, N, et al.
Udgivet: (2003)

Protective effects of imeglimin on the development of atherosclerosis in ApoE KO mice treated with STZ
af: Junpei Sanada, et al.
Udgivet: (2024-03-01)

Long-term oral tetrahydrobiopterin supplementation reduces atherosclerosis in apolipoprotein e knockout mice
af: Schmidt, T, et al.
Udgivet: (2008)

Rapid Effects of Atorvastatin on Tetrahydrobiopterin-Mediated eNOS Coupling in Human Arteries, is Mediated by Stimulation of Vascular GTP-Cyclohydrolase
af: Antoniades, C, et al.
Udgivet: (2011)

A specific role for eNOS-derived reactive oxygen species in atherosclerosis progression.
af: Takaya, T, et al.
Udgivet: (2007)

eNOS protects from atherosclerosis despite relevant superoxide production by the enzyme in apoE mice.
af: Padmapriya Ponnuswamy, et al.
Udgivet: (2012-01-01)

Nitric oxide bioactivity in ApoE -/- mice is maintained by increased endothelial tetrahydrobiopterin synthesis via targeted GTP cyclohydrolase-1 over-expression
af: Alp, N, et al.
Udgivet: (2003)

Gene transfer of a broad spectrum CC-chemokine inhibitor reduces vein graft atherosclerosis in apolipoprotein E-knockout mice.
af: Ali, Z, et al.
Udgivet: (2005)

Correction of tetrahydrobiopterin deficiency - Implications for dopa responsive dystonia and other inherited disorders of tetrahydrobiopterin metabolism
af: Heales, S, et al.
Udgivet: (2005)

Tetrahydrobiopterin Slows the Progression of Atherosclerosis
af: Kunihiro Suzuki, et al.
Udgivet: (2007-02-01)