Genome-scale methods converge on key mitochondrial genes for the survival of human cardiomyocytes in hypoxia.
BACKGROUND: Any reduction in myocardial oxygen delivery relative to its demands can impair cardiac contractile performance. Understanding the mitochondrial metabolic response to hypoxia is key to understanding ischemia tolerance in the myocardium. We used a novel combination of 2 genome-scale method...
Autors principals: | Edwards, L, Sigurdsson, M, Robbins, P, Weale, M, Cavalleri, G, Montgomery, H, Thiele, I |
---|---|
Format: | Journal article |
Idioma: | English |
Publicat: |
2014
|
Ítems similars
-
Changes of mitochondrial pathway in hypoxia/reoxygenation induced cardiomyocytes apoptosis.
per: Tielong Chen, et al.
Publicat: (2008-01-01) -
Shock Wave Therapy Promotes Cardiomyocyte Autophagy and Survival during Hypoxia
per: Ling Du, et al.
Publicat: (2017-06-01) -
Sevoflurane postconditioning attenuates cardiomyocyte hypoxia/reoxygenation injury via restoring mitochondrial morphology
per: Jin Yu, et al.
Publicat: (2016-11-01) -
Fatty acids composition of inner mitochondrial membrane of rat cardiomyocytes and hepatocytes during hypoxia-hypercapnia
per: S. V. Khyzhnyak, et al.
Publicat: (2016-06-01) -
Retraction: Opa1 reduces hypoxia-induced cardiomyocyte death by improving mitochondrial quality control
per: Frontiers Editorial Office
Publicat: (2022-08-01)