Genome-scale methods converge on key mitochondrial genes for the survival of human cardiomyocytes in hypoxia.

Genome-scale methods converge on key mitochondrial genes for the survival of human cardiomyocytes in hypoxia.

BACKGROUND: Any reduction in myocardial oxygen delivery relative to its demands can impair cardiac contractile performance. Understanding the mitochondrial metabolic response to hypoxia is key to understanding ischemia tolerance in the myocardium. We used a novel combination of 2 genome-scale method...

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Dettagli Bibliografici
Autori principali:	Edwards, L, Sigurdsson, M, Robbins, P, Weale, M, Cavalleri, G, Montgomery, H, Thiele, I
Natura:	Journal article
Lingua:	English
Pubblicazione:	2014

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