A novel image-based high throughput screening assay discovers therapeutic candidates for adult polyglucosan body disease
Glycogen storage disorders (GSDs) are caused by excessive accumulation of glycogen. Some GSDs (Adult Polyglucosan Body Disease (APBD), Tarui and Lafora diseases) are caused by intracellular accumulation of insoluble inclusions, called polyglucosan bodies (PB), which are chiefly composed of malconstr...
المؤلفون الرئيسيون: | Solmesky, L, Khazanov, N, Senderowitz, H, Wang, P, Minassian, B, Ferreira, I, Yue, W, Lossos, A, Weil, M, Kakhlon, O |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
Portland Press
2017
|
مواد مشابهة
-
Guaiacol as a drug candidate for treating adult polyglucosan body disease
حسب: Kakhlon, O, وآخرون
منشور في: (2018) -
Alleviation of a polyglucosan storage disorder by enhancement of autophagic glycogen catabolism
حسب: Or Kakhlon, وآخرون
منشور في: (2021-09-01) -
Polyglucosan bodies in medullary catecholaminergic neurons in SUDEP
حسب: Smriti Patodia, وآخرون
منشور في: (2021-01-01) -
Amylopectinosis of the fatal epilepsy Lafora disease resists autophagic glycogen catabolism
حسب: Jun Wu, وآخرون
منشور في: (2024-04-01) -
GYG1: A distal myopathy with polyglucosan bodies
حسب: Stefan Nicolau, وآخرون
منشور في: (2020-09-01)