Trading N and O. Part 2: Exploiting aziridinium intermediates for the synthesis of β-hydroxy-α-amino acids
The β-hydroxy-α-amino acids (S,S)-allo-threonine, (S,S)-β-hydroxyleucine and a range of aryl substituted (S,S)-β-hydroxyphenylalanines were prepared from the corresponding enantiopure anti-α-hydroxy-β-amino esters via a rearrangement protocol, which proceeds via the intermediacy of the corresponding...
Үндсэн зохиолчид: | Davies, S, Fletcher, A, Frost, AB, Roberts, P, Thomson, J |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
Elsevier
2014
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Ижил төстэй зүйлс
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Aziridines and aziridinium intermediates in the asymmetric synthesis of beta-substituted-alpha-amino acids and 1,2,3,4-tetrahydroisoquinolines
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