Alien limb following posterior cerebral artery stroke: failure to recognize internally generated movements?
We describe two rare cases of alien limb syndrome following right posterior cerebral artery (PCA) stroke. Both patients present with left hemianopia, visual neglect and proprioceptive loss in addition to their alien limb symptoms. Lesion subtraction from seven control PCA patients revealed that medi...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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2007
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| _version_ | 1826300100562911232 |
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| author | Coulthard, E Rudd, A Playford, E Husain, M |
| author_facet | Coulthard, E Rudd, A Playford, E Husain, M |
| author_sort | Coulthard, E |
| collection | OXFORD |
| description | We describe two rare cases of alien limb syndrome following right posterior cerebral artery (PCA) stroke. Both patients present with left hemianopia, visual neglect and proprioceptive loss in addition to their alien limb symptoms. Lesion subtraction from seven control PCA patients revealed that medial parietal-occipital and thalamic areas were selectively damaged in the alien limb patients. We propose that loss of the sense of motor intention and internal model of the current state of the arm, combined with deficient proprioceptive and visual feedback of the moving limb, are critical for genesis of posterior alien limb and discuss how affected regions normally function to ensure awareness of self-generated motor activity. |
| first_indexed | 2024-03-07T05:12:01Z |
| format | Journal article |
| id | oxford-uuid:dbe1b449-9f70-4f7d-8857-b2c0dd366144 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:12:01Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:dbe1b449-9f70-4f7d-8857-b2c0dd3661442022-03-27T09:13:48ZAlien limb following posterior cerebral artery stroke: failure to recognize internally generated movements?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:dbe1b449-9f70-4f7d-8857-b2c0dd366144EnglishSymplectic Elements at Oxford2007Coulthard, ERudd, APlayford, EHusain, MWe describe two rare cases of alien limb syndrome following right posterior cerebral artery (PCA) stroke. Both patients present with left hemianopia, visual neglect and proprioceptive loss in addition to their alien limb symptoms. Lesion subtraction from seven control PCA patients revealed that medial parietal-occipital and thalamic areas were selectively damaged in the alien limb patients. We propose that loss of the sense of motor intention and internal model of the current state of the arm, combined with deficient proprioceptive and visual feedback of the moving limb, are critical for genesis of posterior alien limb and discuss how affected regions normally function to ensure awareness of self-generated motor activity. |
| spellingShingle | Coulthard, E Rudd, A Playford, E Husain, M Alien limb following posterior cerebral artery stroke: failure to recognize internally generated movements? |
| title | Alien limb following posterior cerebral artery stroke: failure to recognize internally generated movements? |
| title_full | Alien limb following posterior cerebral artery stroke: failure to recognize internally generated movements? |
| title_fullStr | Alien limb following posterior cerebral artery stroke: failure to recognize internally generated movements? |
| title_full_unstemmed | Alien limb following posterior cerebral artery stroke: failure to recognize internally generated movements? |
| title_short | Alien limb following posterior cerebral artery stroke: failure to recognize internally generated movements? |
| title_sort | alien limb following posterior cerebral artery stroke failure to recognize internally generated movements |
| work_keys_str_mv | AT coultharde alienlimbfollowingposteriorcerebralarterystrokefailuretorecognizeinternallygeneratedmovements AT rudda alienlimbfollowingposteriorcerebralarterystrokefailuretorecognizeinternallygeneratedmovements AT playforde alienlimbfollowingposteriorcerebralarterystrokefailuretorecognizeinternallygeneratedmovements AT husainm alienlimbfollowingposteriorcerebralarterystrokefailuretorecognizeinternallygeneratedmovements |