Hypoxia-induced chromatin changes and ATM signalling
<p>The DNA damage response (DDR) is a complex signalling cascade triggered in response to stress, in an attempt to maintain genomic integrity. Components of this pathway, such as ATM-mediated signalling, have been proposed to act as a barrier in the early stages of tumourigenesis. Regions o...
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Format: | Thesis |
Language: | English |
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2014
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