Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.

Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.

Base excision repair (BER) is the major cellular pathway involved in removal of endogenous/spontaneous DNA lesions. Here, we study the mechanism that controls the steady-state levels of BER enzymes in human cells. By fractionating human cell extract, we purified the E3 ubiquitin ligase Mule (ARF-BP1...

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Bibliographic Details
Main Authors:	Parsons, J, Tait, P, Finch, D, Dianova, I, Edelmann, M, Khoronenkova, S, Kessler, B, Sharma, R, Mckenna, W, Dianov, G
Format:	Journal article
Language:	English
Published:	2009

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