Fluoroglycoproteins: ready chemical site-selective incorporation of fluorosugars into proteins.

A tag-and-modify strategy allows the practical synthesis of homogenous fluorinated glyco-amino acids, peptides and proteins carrying a fluorine label in the sugar and allows access to first examples of directly radiolabelled ([(18)F]-glyco)proteins.

Dettagli Bibliografici
Autori principali: Boutureira, O, D'Hooge, F, Fernández-González, M, Bernardes, G, Sánchez-Navarro, M, Koeppe, JR, Davis, B
Natura: Journal article
Lingua:English
Pubblicazione: 2010
Descrizione
Riassunto:A tag-and-modify strategy allows the practical synthesis of homogenous fluorinated glyco-amino acids, peptides and proteins carrying a fluorine label in the sugar and allows access to first examples of directly radiolabelled ([(18)F]-glyco)proteins.