Post-operative progress of dystonia patients following globus pallidus internus deep brain stimulation.

In the current era of functional surgery for movement disorders, deep brain stimulation (DBS) of the globus pallidus internus (GPi) is emerging as the favoured intervention for patients with dystonia. Here we report our results in 20 patients with medically intractable dystonia treated with GPi stim...

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Main Authors: Yianni, J, Bain, P, Gregory, R, Nandi, D, Joint, C, Scott, R, Stein, J, Aziz, T
Format: Journal article
Language:English
Published: 2003
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author Yianni, J
Bain, P
Gregory, R
Nandi, D
Joint, C
Scott, R
Stein, J
Aziz, T
author_facet Yianni, J
Bain, P
Gregory, R
Nandi, D
Joint, C
Scott, R
Stein, J
Aziz, T
author_sort Yianni, J
collection OXFORD
description In the current era of functional surgery for movement disorders, deep brain stimulation (DBS) of the globus pallidus internus (GPi) is emerging as the favoured intervention for patients with dystonia. Here we report our results in 20 patients with medically intractable dystonia treated with GPi stimulation. The series comprised 14 patients with generalized dystonia and six with spasmodic torticollis. Although comparisons were limited by differences in their respective neurological rating scales, chronic DBS clearly benefited both patient groups. Data conveying the rate of change in neurological function following intervention are also presented, demonstrating the gradual but progressive and sustained nature of improvement following stimulation of the GPi in dystonic patients.
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spelling oxford-uuid:dc1d5a13-fabb-4956-a7db-4b0e1d4158c12022-03-27T09:15:28ZPost-operative progress of dystonia patients following globus pallidus internus deep brain stimulation.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:dc1d5a13-fabb-4956-a7db-4b0e1d4158c1EnglishSymplectic Elements at Oxford2003Yianni, JBain, PGregory, RNandi, DJoint, CScott, RStein, JAziz, TIn the current era of functional surgery for movement disorders, deep brain stimulation (DBS) of the globus pallidus internus (GPi) is emerging as the favoured intervention for patients with dystonia. Here we report our results in 20 patients with medically intractable dystonia treated with GPi stimulation. The series comprised 14 patients with generalized dystonia and six with spasmodic torticollis. Although comparisons were limited by differences in their respective neurological rating scales, chronic DBS clearly benefited both patient groups. Data conveying the rate of change in neurological function following intervention are also presented, demonstrating the gradual but progressive and sustained nature of improvement following stimulation of the GPi in dystonic patients.
spellingShingle Yianni, J
Bain, P
Gregory, R
Nandi, D
Joint, C
Scott, R
Stein, J
Aziz, T
Post-operative progress of dystonia patients following globus pallidus internus deep brain stimulation.
title Post-operative progress of dystonia patients following globus pallidus internus deep brain stimulation.
title_full Post-operative progress of dystonia patients following globus pallidus internus deep brain stimulation.
title_fullStr Post-operative progress of dystonia patients following globus pallidus internus deep brain stimulation.
title_full_unstemmed Post-operative progress of dystonia patients following globus pallidus internus deep brain stimulation.
title_short Post-operative progress of dystonia patients following globus pallidus internus deep brain stimulation.
title_sort post operative progress of dystonia patients following globus pallidus internus deep brain stimulation
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