New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation.

New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation.

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In this review, we discuss the role of the tumour-associated carbonic anhydrase isoform IX (CAIX) in the context of pH regulation. We summarise recent experimental findings on the effect of CAIX on cell growth and survival, and present a diffusion-reaction model to help in the assessment of CAIX fun...

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Bibliographische Detailangaben
Hauptverfasser:	Swietach, P, Hulikova, A, Vaughan-Jones, R, Harris, A
Format:	Journal article
Sprache:	English
Veröffentlicht:	2010

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