New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation.

New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation.

Diğer sürümleri göster (1)

In this review, we discuss the role of the tumour-associated carbonic anhydrase isoform IX (CAIX) in the context of pH regulation. We summarise recent experimental findings on the effect of CAIX on cell growth and survival, and present a diffusion-reaction model to help in the assessment of CAIX fun...

Detaylı Bibliyografya
Asıl Yazarlar:	Swietach, P, Hulikova, A, Vaughan-Jones, R, Harris, A
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2010

Benzer Materyaller

New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation
Yazar:: Swietach, P, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo
Yazar:: Lee, S-H, ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Carbonic anhydrase IX unifies spatial pH(i) regulation in large cell-clusters
Yazar:: Swietach, P, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Regulation of tumor pH and the role of carbonic anhydrase 9.
Yazar:: Swietach, P, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

The chemistry, physiology and pathology of pH in cancer.
Yazar:: Swietach, P, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Intracellular carbonic anhydrase activity sensitizes cancer cell pH signaling to dynamic changes in CO2 partial pressure
Yazar:: Hulikova, A, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX
Yazar:: Murri-Plesko, M, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX.
Yazar:: Murri-Plesko, M, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

Cancer-associated, hypoxia-inducible carbonic anhydrase IX facilitates CO2 diffusion.
Yazar:: Swietach, P, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths.
Yazar:: Swietach, P, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Regulation of intracellular pH in cancer cell lines under normoxia and hypoxia.
Yazar:: Hulikova, A, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

Acid-extrusion from tissue: the interplay between membrane transporters and pH buffers.
Yazar:: Hulikova, A, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Importance of intracellular pH in determining the uptake and efficacy of the weakly basic chemotherapeutic drug, doxorubicin.
Yazar:: Swietach, P, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Molecular mechanisms of carbonic anhydrase IX-mediated pH regulation under hypoxia.
Yazar:: Pastorekova, S, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Dual role of CO2/HCO3(-) buffer in the regulation of intracellular pH of three-dimensional tumor growths.
Yazar:: Hulikova, A, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths.
Yazar:: Swietach, P, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

Spatial regulation of intracellular pH in multicellular strands of neonatal rat cardiomyocytes.
Yazar:: Swietach, P, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Common inhibitors of membrane H+-transport also inhibit carbonic anhydrase
Yazar:: Villafuerte, F, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors
Yazar:: Olga eSedlakova, ve diğerleri
Baskı/Yayın Bilgisi: (2014-01-01)

Importance of intracellular pH in determining the uptake and efficacy of the weakly basic chemotherapeutic drug, doxorubicin.
Yazar:: Pawel Swietach, ve diğerleri
Baskı/Yayın Bilgisi: (2012-01-01)

Extramitochondrial domain rich in carbonic anhydrase activity improves myocardial energetics.
Yazar:: Schroeder, M, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

The role of soil pH on soil carbonic anhydrase activity
Yazar:: J. Sauze, ve diğerleri
Baskı/Yayın Bilgisi: (2018-01-01)

An Extra-Mitochondrial Domain Rich in Carbonic Anhydrase Activity Improves Myocardial Energetics
Yazar:: Schroeder, M, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy.
Yazar:: McIntyre, A, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Detection of intravascular hemolysis in newborns using urinary carbonic anhydrase I immunoreactivity
Yazar:: Kramer, H, ve diğerleri
Baskı/Yayın Bilgisi: (2020)

Carbonic Anhydrases: Role in pH Control and Cancer
Yazar:: Mam Y. Mboge, ve diğerleri
Baskı/Yayın Bilgisi: (2018-02-01)

Plasmatic exosomes from prostate cancer patients show increased carbonic anhydrase IX expression and activity and low pH
Yazar:: Mariantonia Logozzi, ve diğerleri
Baskı/Yayın Bilgisi: (2020-01-01)

Intracellular pH regulation in heart.
Yazar:: Vaughan-Jones, R, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

Spatial regulation of intracellular pH in the ventricular myocyte.
Yazar:: Swietach, P, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

The inhibitory effect of boric acid on hypoxia-regulated tumour-associated carbonic anhydrase IX
Yazar:: Zainab Saad Yusuf, ve diğerleri
Baskı/Yayın Bilgisi: (2022-12-01)

Differentiation impairs low pH-induced Ca2+ signaling and ERK phosphorylation in granule precursor tumour cells.
Yazar:: Huang, W, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

Targeting Carbonic Anhydrase IX Activity and Expression
Yazar:: Brian P. Mahon, ve diğerleri
Baskı/Yayın Bilgisi: (2015-01-01)

Microsecond Simulation of the Proteoglycan-like Region of Carbonic Anhydrase IX and Design of Chemical Inhibitors Targeting pH Homeostasis in Cancer Cells
Yazar:: Arun John, ve diğerleri
Baskı/Yayın Bilgisi: (2020-02-01)

Gating of cardiac gap junctional channels at acid and alkaline pH
Yazar:: Swietach, P, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Carbonic anhydrase IX in oligodendroglial brain tumors
Yazar:: Pastorekova Silvia, ve diğerleri
Baskı/Yayın Bilgisi: (2008-01-01)

Spatial aspects of intracellular pH regulation in heart muscle.
Yazar:: Vaughan-Jones, R, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

CrossTalk opposing view: Physiological CO2 exchange does not normally depend on membrane channels
Yazar:: Hulikova, A, ve diğerleri
Baskı/Yayın Bilgisi: (2015)

2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms
Yazar:: Lisa Sequeira, ve diğerleri
Baskı/Yayın Bilgisi: (2023-12-01)

The relationship between intracellular pH and proton mobility in rat and guinea-pig ventricular myocytes
Yazar:: Swietach, P, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Relationship between intracellular pH and proton mobility in rat and guinea-pig ventricular myocytes.
Yazar:: Swietach, P, ve diğerleri
Baskı/Yayın Bilgisi: (2005)