New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation.

In this review, we discuss the role of the tumour-associated carbonic anhydrase isoform IX (CAIX) in the context of pH regulation. We summarise recent experimental findings on the effect of CAIX on cell growth and survival, and present a diffusion-reaction model to help in the assessment of CAIX fun...

Полное описание

Библиографические подробности
Главные авторы: Swietach, P, Hulikova, A, Vaughan-Jones, R, Harris, A
Формат: Journal article
Язык:English
Опубликовано: 2010