New insights into the T cell synapse from single molecule techniques.
T cell activation depends on extracellular ligation of the T cell receptor (TCR) by peptide-MHC complexes in a synapse between the T cell and an antigen-presenting cell. The process then requires the assembly of signalling complexes between the TCR and the adaptor protein linker for activation of T...
Main Authors: | Dustin, M, Depoil, D |
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Format: | Journal article |
Language: | English |
Published: |
2011
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