Effects of cigarette smoking on quinine pharmacokinetics in malaria.
OBJECTIVE: Quinine is an important antimalarial drug that is metabolised mainly by the hepatic mixed-function microsomal enzyme cytochrome P(450). Cigarette smoking in healthy volunteers has been reported to enhance quinine clearance. The present study evaluated the effects of smoking on quinine pha...
| Main Authors: | , , , , , |
|---|---|
| Format: | Journal article |
| Sprog: | English |
| Udgivet: |
2002
|