Drosophila SnoN modulates growth and patterning by antagonizing TGF-beta signalling.

Drosophila SnoN modulates growth and patterning by antagonizing TGF-beta signalling.

Signalling by TGF-beta ligands through the Smad family of transcription factors is critical for developmental patterning and growth. Disruption of this pathway has been observed in various cancers. In vertebrates, members of the Ski/Sno protein family can act as negative regulators of TGF-beta signa...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Ramel, M, Emery, C, Foulger, R, Goberdhan, D, van den Heuvel, M, Wilson, C
Format:	Journal article
Sprache:	English
Veröffentlicht:	2007

Ähnliche Einträge

Drosophila SnoN modulates growth and patterning by antagonizing TGF-beta signalling (vol 124, pg 304, 2007)
von: Ramel, M, et al.
Veröffentlicht: (2007)

Drosophila SnoN modulates growth and patterning by antagonizing TGF-β signalling [Mech. Dev. 124 (2007) 304-317] (DOI:10.1016/j.mod.2006.12.006)
von: Ramel, M, et al.
Veröffentlicht: (2007)

TGF-β Repressors SnoN and Ski Are Implicated in Human Colorectal Carcinogenesis
von: Vasiliki Bravou, et al.
Veröffentlicht: (2009-01-01)

SKIL/SnoN attenuates TGF-β1/SMAD signaling-dependent collagen synthesis in hepatic fibrosis
von: Cheng Chi, et al.
Veröffentlicht: (2023-11-01)

SnoN upregulation ameliorates renal fibrosis in diabetic nephropathy.
von: Lirong Liu, et al.
Veröffentlicht: (2017-01-01)

Efficient TGF-β/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression
von: Alexaki Vasileia I, et al.
Veröffentlicht: (2011-01-01)

Jiangtang Tongmai Prescription Reduced Diabetic Lung Injury Through SnoN and TGF-β1/Smads Signaling Pathway
von: Nian Ding, et al.
Veröffentlicht: (2022-06-01)

Herbal compound 861 prevents hepatic fibrosis by inhibiting the TGF-β1/Smad/SnoN pathway in bile duct-ligated rats
von: Cheng Chi, et al.
Veröffentlicht: (2018-02-01)

A misexpression screen to identify novel regulators of growth and proliferation in Drosophila.
von: Foulger, R, et al.
Veröffentlicht: (2001)

Oxymatrine Inhibits Renal Tubular EMT Induced by High Glucose via Upregulation of SnoN and Inhibition of TGF-β1/Smad Signaling Pathway.
von: Lirong Liu, et al.
Veröffentlicht: (2016-01-01)

The Sno oncogene antagonizes Wingless signaling during wing development in Drosophila.
von: Janine C Quijano, et al.
Veröffentlicht: (2010-07-01)

The crystal structure of the Dachshund domain of human SnoN reveals flexibility in the putative protein interaction surface.
von: Tomas Nyman, et al.
Veröffentlicht: (2010-09-01)

Sumoylated SnoN interacts with HDAC1 and p300/CBP to regulate EMT-associated phenotypes in mammary organoids
von: Ayan Chanda, et al.
Veröffentlicht: (2023-07-01)

Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway.
von: Goberdhan, D, et al.
Veröffentlicht: (1999)

BMP-7 ameliorates partial epithelial-mesenchymal transition by restoring SnoN protein level via Smad1/5 pathway in diabetic kidney disease
von: Wei Peng, et al.
Veröffentlicht: (2022-03-01)

The functions of insulin signaling: size isn't everything, even in Drosophila.
von: Goberdhan, D, et al.
Veröffentlicht: (2003)

Insulin receptor-mediated organ overgrowth in Drosophila is not restricted by body size.
von: Goberdhan, D, et al.
Veröffentlicht: (2002)

JNK, cytoskeletal regulator and stress response kinase? A Drosophila perspective.
von: Goberdhan, D, et al.
Veröffentlicht: (1998)

CDK12 antagonizes a viral suppressor of RNAi to modulate antiviral RNAi in Drosophila
von: Liqin Zhang, et al.
Veröffentlicht: (2025-01-01)

Erratum: A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila (Genes and Development (1996) 10 (2745- 2758))
von: Wilson, C, et al.
Veröffentlicht: (1997)

The Drosophila TGF-beta/Activin-like ligands Dawdle and Myoglianin appear to modulate adult lifespan through regulation of 26S proteasome function in adult muscle
von: Shaughna Langerak, et al.
Veröffentlicht: (2018-04-01)

The Drosophila accessory gland as a model for prostate cancer and other pathologies
von: Wilson, C, et al.
Veröffentlicht: (2016)

Nubbin isoform antagonism governs Drosophila intestinal immune homeostasis.
von: Bo G Lindberg, et al.
Veröffentlicht: (2018-03-01)

Distribution of transforming growth factor-beta isoforms TGF-beta 1, TGF-beta 2 and TGF-beta 3 and vascular endothelial growth factor in vulvar lichen sclerosus.
von: Farrell, A, et al.
Veröffentlicht: (2001)

The protein phosphatase PP2A-B' subunit Widerborst is a negative regulator of cytoplasmic activated Akt and lipid metabolism in Drosophila.
von: Vereshchagina, N, et al.
Veröffentlicht: (2008)

mTORC1 signalling mediates PI3K-dependent large lipid droplet accumulation in Drosophila ovarian nurse cells
von: Mensah, L, et al.
Veröffentlicht: (2017)

Neutrinoless Double Beta Decay in the SNO+ Experiment
von: Paton, J
Veröffentlicht: (2019)

Neutrinoless double beta decay search with SNO+
von: Lozza V.
Veröffentlicht: (2014-01-01)

Dror, a potential neurotrophic receptor gene, encodes a Drosophila homolog of the vertebrate Ror family of Trk-related receptor tyrosine kinases.
von: Wilson, C, et al.
Veröffentlicht: (1993)

SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis
von: Xiaolong Tang, et al.
Veröffentlicht: (2017-08-01)

Transforming growth factor β<sub>1 </sub>inhibits bone morphogenic protein (BMP)-2 and BMP-7 signaling via upregulation of Ski-related novel protein N (SnoN): possible mechanism for the failure of BMP therapy?
von: Ehnert Sabrina, et al.
Veröffentlicht: (2012-09-01)

Abstract 2: Epigenetic Modulation of TGF-beta Signaling Underlies the Scarring Fibroblast Phenotype
von: Heather E. desJardins-Park, AB, et al.
Veröffentlicht: (2019-04-01)

Reduced SMAD7 leads to overactivation of TGF-beta signaling in MDS that can be reversed by a specific inhibitor of TGF-beta receptor I kinase.
von: Zhou, L, et al.
Veröffentlicht: (2011)

Protocol for efficient human MSC chondrogenesis via Wnt antagonism instead of TGF-β
von: Chen-Chan Hsieh, et al.
Veröffentlicht: (2023-12-01)

TGFβ-facilitated optic fissure fusion and the role of bone morphogenetic protein antagonism
von: Max D. Knickmeyer, et al.
Veröffentlicht: (2018-03-01)

Opioid antagonism modulates wanting-related frontostriatal connectivity
von: Alexander Soutschek, et al.
Veröffentlicht: (2021-11-01)

TGF-Beta Modulates the Integrity of the Blood Brain Barrier In Vitro, and Is Associated with Metabolic Alterations in Pericytes
von: Leonie Schumacher, et al.
Veröffentlicht: (2023-01-01)

Expression and regulation of the TGF-beta-activating integrin alpha(v)beta(8) on human dendritic cells
von: Fenton, T, et al.
Veröffentlicht: (2013)

Altered expression of TGF alpha and TGF beta 1 in the mucosa of the functioning pelvic ileal pouch.
von: Campbell, A, et al.
Veröffentlicht: (1996)

Metapopulation structure modulates sexual antagonism
von: E. Rodriguez‐Exposito, et al.
Veröffentlicht: (2021-08-01)