Penicillin binding protein substitutions co-occur with fluoroquinolone resistance in ‘epidemic’ lineages of multi drug-resistant Clostridioides difficile
Clostridioides difficile remains a key cause of healthcare-associated infection, with multidrug-resistant (MDR) lineages causing high-mortality (≥20%) outbreaks. Cephalosporin treatment is a long-established risk factor, and antimicrobial stewardship is a key control. A mechanism underlying raised c...
| Main Authors: | , , , , , , , , , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
American Society for Microbiology
2023
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