Resistance mechanisms to mTOR inhibition in renal cancer
<p><b>Introduction</b>: Advanced clear cell renal cell cancer (CCRCC) is incurable, but molecularly targeted treatments have improved the prognosis. One such molecular target is the mammalian target of rapamycin (mTOR) and two rapalogues (everolimus and temsirolimus) have been lice...
Glavni avtor: | Earwaker, P |
---|---|
Drugi avtorji: | Macaulay, V |
Format: | Thesis |
Jezik: | English |
Izdano: |
2015
|
Podobne knjige/članki
-
The effects of mTOR inhibition in ischemic stroke
od: Schneider, AM
Izdano: (2022) -
RAPTOR up-regulation contributes to resistance of renal cancer cells to PI3K-mTOR inhibition PONE-D-17-28641
od: Earwa, P, et al.
Izdano: (2018) -
Influenza vaccines: mTOR inhibition surprisingly leads to protection.
od: Mcmichael, A, et al.
Izdano: (2013) -
Insights into the regulation of mTOR signaling and the consequences of pharmacological inhibition
od: Thoreen, Carson Cornell
Izdano: (2009) -
Reversal of phenotypes of cellular senescence by pan-mTOR inhibition
od: Cox, L, et al.
Izdano: (2016)