Five-year cost-effectiveness analysis of the European Fans in Training (EuroFIT) physical activity intervention for men versus no intervention
<p>Objectives</p> <p>Increasing physical activity reduces the risk of chronic illness including Type 2 diabetes, cardiovascular disease and certain types of cancer. Lifestyle interventions can increase physical activity but few successfully engage men. This study aims to investigat...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
BMC
2020
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| _version_ | 1797098703971942400 |
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| author | Kolovos, S Finch, AP van der Ploeg, H van Nassau, F Broulikova, HM Baka, A Treweek, S Gray, CM Jelsma, JGM Bunn, C Roberts, GC Silva, MN Gill, JMR Røynesdal, Ø van Mechelen, W Andersen, E Hunt, K Wyke, S Bosmans, JE |
| author_facet | Kolovos, S Finch, AP van der Ploeg, H van Nassau, F Broulikova, HM Baka, A Treweek, S Gray, CM Jelsma, JGM Bunn, C Roberts, GC Silva, MN Gill, JMR Røynesdal, Ø van Mechelen, W Andersen, E Hunt, K Wyke, S Bosmans, JE |
| author_sort | Kolovos, S |
| collection | OXFORD |
| description | <p>Objectives</p>
<p>Increasing physical activity reduces the risk of chronic illness including Type 2 diabetes, cardiovascular disease and certain types of cancer. Lifestyle interventions can increase physical activity but few successfully engage men. This study aims to investigate the 5 year cost-effectiveness of EuroFIT, a program to improve physical activity tailored specifically for male football (soccer) fans compared to a no intervention comparison group.</p>
<br>
<p>Methods</p>
<p>We developed a Markov cohort model in which the impact of improving physical activity on five chronic health conditions (colorectal cancer, Type 2 diabetes, coronary heart disease, stroke and depression) and mortality was modelled. We estimated costs from a societal perspective and expressed benefits as quality adjusted life years (QALYs). We obtained data from a 4-country (England, Netherlands, Portugal and Norway) pragmatic randomised controlled trial evaluating EuroFIT, epidemiological and cohort studies, and meta-analyses. We performed deterministic and probabilistic sensitivity analyses to assess the impact of uncertainty in the model’s parameter values on the cost-effectiveness results. We used Monte Carlo simulations to estimate uncertainty and presented this using cost-effectiveness acceptability curves (CEACs). We tested the robustness of the base case analysis using five scenario analyses.</p>
<br>
<p>Results</p>
<p>Average costs over 5 years per person receiving EuroFIT were €14,663 and per person receiving no intervention €14,598. Mean QALYs over 5 years were 4.05 per person for EuroFIT and 4.04 for no intervention. Thus, the average incremental cost per person receiving EuroFIT was €65 compared to no intervention, while the average QALY gain was 0.01. This resulted in an ICER of €5206 per QALY gained. CEACs show that the probability of EuroFIT being cost-effective compared to no intervention is 0.53, 0.56 and 0.58 at thresholds of €10,000, €22,000 and €34,000 per QALY gained, respectively. When using a time horizon of 10 years, the results suggest that EuroFIT is more effective and less expensive compared to (i.e. dominant over) no intervention with a probability of cost-effectiveness of 0.63 at a threshold of €22,000 per QALY gained.</p>
<br>
<p>Conclusions</p>
<p>We conclude the EuroFIT intervention is not cost-effective compared to no intervention over a period of 5 years from a societal perspective, but is more effective and less expensive (i.e. dominant) after 10 years. We thus suggest that EuroFIT can potentially improve public health in a cost-effective manner in the long term.</p> |
| first_indexed | 2024-03-07T05:13:25Z |
| format | Journal article |
| id | oxford-uuid:dc545be5-eee9-46df-95e1-b011f84f6bc6 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T05:13:25Z |
| publishDate | 2020 |
| publisher | BMC |
| record_format | dspace |
| spelling | oxford-uuid:dc545be5-eee9-46df-95e1-b011f84f6bc62022-03-27T09:17:11ZFive-year cost-effectiveness analysis of the European Fans in Training (EuroFIT) physical activity intervention for men versus no interventionJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:dc545be5-eee9-46df-95e1-b011f84f6bc6Symplectic ElementsBMC2020Kolovos, SFinch, APvan der Ploeg, Hvan Nassau, FBroulikova, HMBaka, ATreweek, SGray, CMJelsma, JGMBunn, CRoberts, GCSilva, MNGill, JMRRøynesdal, Øvan Mechelen, WAndersen, EHunt, KWyke, SBosmans, JE<p>Objectives</p> <p>Increasing physical activity reduces the risk of chronic illness including Type 2 diabetes, cardiovascular disease and certain types of cancer. Lifestyle interventions can increase physical activity but few successfully engage men. This study aims to investigate the 5 year cost-effectiveness of EuroFIT, a program to improve physical activity tailored specifically for male football (soccer) fans compared to a no intervention comparison group.</p> <br> <p>Methods</p> <p>We developed a Markov cohort model in which the impact of improving physical activity on five chronic health conditions (colorectal cancer, Type 2 diabetes, coronary heart disease, stroke and depression) and mortality was modelled. We estimated costs from a societal perspective and expressed benefits as quality adjusted life years (QALYs). We obtained data from a 4-country (England, Netherlands, Portugal and Norway) pragmatic randomised controlled trial evaluating EuroFIT, epidemiological and cohort studies, and meta-analyses. We performed deterministic and probabilistic sensitivity analyses to assess the impact of uncertainty in the model’s parameter values on the cost-effectiveness results. We used Monte Carlo simulations to estimate uncertainty and presented this using cost-effectiveness acceptability curves (CEACs). We tested the robustness of the base case analysis using five scenario analyses.</p> <br> <p>Results</p> <p>Average costs over 5 years per person receiving EuroFIT were €14,663 and per person receiving no intervention €14,598. Mean QALYs over 5 years were 4.05 per person for EuroFIT and 4.04 for no intervention. Thus, the average incremental cost per person receiving EuroFIT was €65 compared to no intervention, while the average QALY gain was 0.01. This resulted in an ICER of €5206 per QALY gained. CEACs show that the probability of EuroFIT being cost-effective compared to no intervention is 0.53, 0.56 and 0.58 at thresholds of €10,000, €22,000 and €34,000 per QALY gained, respectively. When using a time horizon of 10 years, the results suggest that EuroFIT is more effective and less expensive compared to (i.e. dominant over) no intervention with a probability of cost-effectiveness of 0.63 at a threshold of €22,000 per QALY gained.</p> <br> <p>Conclusions</p> <p>We conclude the EuroFIT intervention is not cost-effective compared to no intervention over a period of 5 years from a societal perspective, but is more effective and less expensive (i.e. dominant) after 10 years. We thus suggest that EuroFIT can potentially improve public health in a cost-effective manner in the long term.</p> |
| spellingShingle | Kolovos, S Finch, AP van der Ploeg, H van Nassau, F Broulikova, HM Baka, A Treweek, S Gray, CM Jelsma, JGM Bunn, C Roberts, GC Silva, MN Gill, JMR Røynesdal, Ø van Mechelen, W Andersen, E Hunt, K Wyke, S Bosmans, JE Five-year cost-effectiveness analysis of the European Fans in Training (EuroFIT) physical activity intervention for men versus no intervention |
| title | Five-year cost-effectiveness analysis of the European Fans in Training (EuroFIT) physical activity intervention for men versus no intervention |
| title_full | Five-year cost-effectiveness analysis of the European Fans in Training (EuroFIT) physical activity intervention for men versus no intervention |
| title_fullStr | Five-year cost-effectiveness analysis of the European Fans in Training (EuroFIT) physical activity intervention for men versus no intervention |
| title_full_unstemmed | Five-year cost-effectiveness analysis of the European Fans in Training (EuroFIT) physical activity intervention for men versus no intervention |
| title_short | Five-year cost-effectiveness analysis of the European Fans in Training (EuroFIT) physical activity intervention for men versus no intervention |
| title_sort | five year cost effectiveness analysis of the european fans in training eurofit physical activity intervention for men versus no intervention |
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