Chondrocyte expansion is associated with loss of primary cilia and disrupted hedgehog signalling
Tissue engineering-based therapies targeting cartilage diseases, such as osteoarthritis, require in vitro expansion of articular chondrocytes. A major obstacle for these therapies is the dedifferentiation and loss of phenotype accompanying chondrocyte expansion. Recent studies suggest that manipulat...
المؤلفون الرئيسيون: | Thompson, C, Plant, J, Wann, A, Bishop, C, Novak, P, Mitchison, H, Beales, P, Chapple, J, Knight, M |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
AO Research Institute Davos
2017
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مواد مشابهة
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Chondrocyte expansion is associated with loss of primary cilia and disrupted hedgehog signalling
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