Chondrocyte expansion is associated with loss of primary cilia and disrupted hedgehog signalling

Chondrocyte expansion is associated with loss of primary cilia and disrupted hedgehog signalling

Tissue engineering-based therapies targeting cartilage diseases, such as osteoarthritis, require in vitro expansion of articular chondrocytes. A major obstacle for these therapies is the dedifferentiation and loss of phenotype accompanying chondrocyte expansion. Recent studies suggest that manipulat...

Podrobná bibliografie
Hlavní autoři:	Thompson, C, Plant, J, Wann, A, Bishop, C, Novak, P, Mitchison, H, Beales, P, Chapple, J, Knight, M
Médium:	Journal article
Jazyk:	English
Vydáno:	AO Research Institute Davos 2017

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