Chondrocyte expansion is associated with loss of primary cilia and disrupted hedgehog signalling

Chondrocyte expansion is associated with loss of primary cilia and disrupted hedgehog signalling

Tissue engineering-based therapies targeting cartilage diseases, such as osteoarthritis, require in vitro expansion of articular chondrocytes. A major obstacle for these therapies is the dedifferentiation and loss of phenotype accompanying chondrocyte expansion. Recent studies suggest that manipulat...

書目詳細資料
Main Authors:	Thompson, C, Plant, J, Wann, A, Bishop, C, Novak, P, Mitchison, H, Beales, P, Chapple, J, Knight, M
格式:	Journal article
語言:	English
出版:	AO Research Institute Davos 2017

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