High performance computer simulations of cardiac electrical function based on high resolution MRI datasets

In this paper, we present a set of applications that allow performance of electrophysiological simulations on individualized models generated using high-resolution MRI data of rabbit hearts. For this purpose, we propose a pipeline consisting of: extraction of significant structures from the images,...

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Main Authors: Plotkowiak, M, Rodriguez, B, Plank, G, Schneider, J, Gavaghan, D, Kohl, P, Grau, V
Format: Conference item
Published: 2008
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author Plotkowiak, M
Rodriguez, B
Plank, G
Schneider, J
Gavaghan, D
Kohl, P
Grau, V
author_facet Plotkowiak, M
Rodriguez, B
Plank, G
Schneider, J
Gavaghan, D
Kohl, P
Grau, V
author_sort Plotkowiak, M
collection OXFORD
description In this paper, we present a set of applications that allow performance of electrophysiological simulations on individualized models generated using high-resolution MRI data of rabbit hearts. For this purpose, we propose a pipeline consisting of: extraction of significant structures from the images, generation of meshes, and application of an electrophysiological solver. In order to make it as useful as possible, we impose several requirements on the development of the pipeline. It has to be fast, aiming towards real time in the future. As much as possible, it must use non-commercial, freely available software (mostly open source). In order to verify the methodology, a set of high resolution MRI images of a rabbit heart is investigated and tested; results are presented in this work. © 2008 Springer-Verlag Berlin Heidelberg.
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spelling oxford-uuid:dc75b353-1134-4ab0-a44b-232cc3e47fd92022-03-27T09:17:55ZHigh performance computer simulations of cardiac electrical function based on high resolution MRI datasetsConference itemhttp://purl.org/coar/resource_type/c_5794uuid:dc75b353-1134-4ab0-a44b-232cc3e47fd9Symplectic Elements at Oxford2008Plotkowiak, MRodriguez, BPlank, GSchneider, JGavaghan, DKohl, PGrau, VIn this paper, we present a set of applications that allow performance of electrophysiological simulations on individualized models generated using high-resolution MRI data of rabbit hearts. For this purpose, we propose a pipeline consisting of: extraction of significant structures from the images, generation of meshes, and application of an electrophysiological solver. In order to make it as useful as possible, we impose several requirements on the development of the pipeline. It has to be fast, aiming towards real time in the future. As much as possible, it must use non-commercial, freely available software (mostly open source). In order to verify the methodology, a set of high resolution MRI images of a rabbit heart is investigated and tested; results are presented in this work. © 2008 Springer-Verlag Berlin Heidelberg.
spellingShingle Plotkowiak, M
Rodriguez, B
Plank, G
Schneider, J
Gavaghan, D
Kohl, P
Grau, V
High performance computer simulations of cardiac electrical function based on high resolution MRI datasets
title High performance computer simulations of cardiac electrical function based on high resolution MRI datasets
title_full High performance computer simulations of cardiac electrical function based on high resolution MRI datasets
title_fullStr High performance computer simulations of cardiac electrical function based on high resolution MRI datasets
title_full_unstemmed High performance computer simulations of cardiac electrical function based on high resolution MRI datasets
title_short High performance computer simulations of cardiac electrical function based on high resolution MRI datasets
title_sort high performance computer simulations of cardiac electrical function based on high resolution mri datasets
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