Activation of the lectin pathway by natural IgM in a model of ischemia/reperfusion injury.

Reperfusion of ischemic tissues elicits an acute inflammatory response involving serum complement, which is activated by circulating natural IgM specific to self-Ags exposed by ischemia. Recent reports demonstrating a role for the lectin pathway raise a question regarding the initial events in compl...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhang, M, Takahashi, K, Alicot, E, Vorup-Jensen, T, Kessler, B, Thiel, S, Jensenius, J, Ezekowitz, R, Moore, F, Carroll, M
Materialtyp: Journal article
Språk:English
Publicerad: 2006