Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence
CD1a molecules on skin Langerhans cells that present self and microbial lipids to T cells have been implicated in the maintenance of skin barrier function. We identified two healthy Vietnamese siblings with a complete lack of surface CD1a expression. Both individuals showed a rare single nucleotide...
| Hlavní autoři: | , , , , , , , , , , , , , , |
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| Médium: | Journal article |
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Elsevier
2016
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