Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence

CD1a molecules on skin Langerhans cells that present self and microbial lipids to T cells have been implicated in the maintenance of skin barrier function. We identified two healthy Vietnamese siblings with a complete lack of surface CD1a expression. Both individuals showed a rare single nucleotide...

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Main Authors:	Cerny, D, Thi Le, D, The, T, Zuest, R, Kg, S, Velumani, S, Khor, C, Mori, L, Simmons, C, Poidinger, M, Zolezzi, F, Ginhoux, F, Haniffa, M, Wills, B, Fink, K
Format:	Journal article
Published:	Elsevier 2016

Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence. by Cerny, D, Thi Le, D, The, T, Zuest, R, Kg, S, Velumani, S, Khor, C, Mori, L, Simmons, C, Poidinger, M, Zolezzi, F, Ginhoux, F, Haniffa, M, Wills, B, Fink, K

Published 2016

Journal article

Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence

Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence. by Cerny, D, Thi Le, D, The, T, Zuest, R, Kg, S, Velumani, S, Khor, C, Mori, L, Simmons, C, Poidinger, M, Zolezzi, F, Ginhoux, F, Haniffa, M, Wills, B, Fink, K

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