Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia

Recent advances in single-cell transcriptomics are ideally placed to unravel intratumoral heterogeneity and selective resistance of cancer stem cell (SC) subpopulations to molecularly targeted cancer therapies. However, current single-cell RNA-sequencing approaches lack the sensitivity required to r...

Full description

Bibliographic Details
Main Authors: Giustacchini, A, Thongjuea, S, Barkas, N, Woll, P, Povinelli, B, Booth, C, Sopp, P, Norfo, R, Rodriguez-Meira, A, Ashley, N, Jamieson, L, Vyas, P, Anderson, K, Segerstolpe, Å, Qian, H, Olsson-Strömberg, U, Mustjoki, S, Sandberg, R, Jacobsen, S, Mead, A
Format: Journal article
Language:English
Published: Nature Publishing Group 2017