What can be done to prevent graft versus host disease?
Graft versus host disease presents a major obstacle to the widespread application of allogeneic bone marrow transplantation despite improvements in drug prophylaxis. Although animal models are providing an understanding of the biology of the process, opportunities for exploitation of that knowledge...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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1994
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| _version_ | 1826300256408567808 |
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| author | Waldmann, H Cobbold, S Hale, G |
| author_facet | Waldmann, H Cobbold, S Hale, G |
| author_sort | Waldmann, H |
| collection | OXFORD |
| description | Graft versus host disease presents a major obstacle to the widespread application of allogeneic bone marrow transplantation despite improvements in drug prophylaxis. Although animal models are providing an understanding of the biology of the process, opportunities for exploitation of that knowledge for therapeutic purposes are still limited. One way to overcome this impasse is to build on the positive benefits of T-cell purging of marrow, by combining it with intelligent correction of the known negative effects. |
| first_indexed | 2024-03-07T05:14:25Z |
| format | Journal article |
| id | oxford-uuid:dcaccdad-4a76-485b-bf3b-3a9a77e14e47 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:14:25Z |
| publishDate | 1994 |
| record_format | dspace |
| spelling | oxford-uuid:dcaccdad-4a76-485b-bf3b-3a9a77e14e472022-03-27T09:19:21ZWhat can be done to prevent graft versus host disease?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:dcaccdad-4a76-485b-bf3b-3a9a77e14e47EnglishSymplectic Elements at Oxford1994Waldmann, HCobbold, SHale, GGraft versus host disease presents a major obstacle to the widespread application of allogeneic bone marrow transplantation despite improvements in drug prophylaxis. Although animal models are providing an understanding of the biology of the process, opportunities for exploitation of that knowledge for therapeutic purposes are still limited. One way to overcome this impasse is to build on the positive benefits of T-cell purging of marrow, by combining it with intelligent correction of the known negative effects. |
| spellingShingle | Waldmann, H Cobbold, S Hale, G What can be done to prevent graft versus host disease? |
| title | What can be done to prevent graft versus host disease? |
| title_full | What can be done to prevent graft versus host disease? |
| title_fullStr | What can be done to prevent graft versus host disease? |
| title_full_unstemmed | What can be done to prevent graft versus host disease? |
| title_short | What can be done to prevent graft versus host disease? |
| title_sort | what can be done to prevent graft versus host disease |
| work_keys_str_mv | AT waldmannh whatcanbedonetopreventgraftversushostdisease AT cobbolds whatcanbedonetopreventgraftversushostdisease AT haleg whatcanbedonetopreventgraftversushostdisease |